This novel title explores the central and peripheral nervous system in health and disease. By first establishing a fundamental basic science knowledge about the cellular elements of the nervous system, the reader is then presented with clinical cases in a pathophysiologic manner, as exemplified in unifying Guillain Barre and Multiple Sclerosis in one chapter on Demyelinating Disease. The reader is encouraged to adopt a systematic approach of sorting out neurologic problems he or she may face in clinical practice by identifying time and space factors based on the age of a patient. High quality illustrations for each case are included in the book along with novel three-dimensional reconstructions of MR, PET, and CT data whenever possible. Developed largely for medical students as an introduction to the clinical neurosciences, for neurology residents, and for others doing graduate level neuroscience study, Neurology - A Modern, Pathophysiologic Approach to the Diagnosis and Treatment of Neurologic Disease will also be of significant interest to the established neurologist as a comprehensive, up-to-date reference.

Dr. Meyer is Editor-In-Chief for NEUROLOGY INTERNATIONAL and currently serves as co-director of Neurosciences for the Guthrie Clinic after being the Medical Director for Neurology and Stroke Services for Sisters Hospital and the St. Joseph's Hospital Campus, Buffalo, NY. Dr. Meyer was a Principal Investigator for the NINDS tPA trial and co-authored the landmark New England Journal of Medicine article on tPA for acute stroke. Prior to directing Neurological Services for Tennova Health Care, Dr. Meyer was a member of the Acute Stroke Team for Catholic Health in Buffalo NY and had served as Chief of Neurology and Stroke Services for the Erie County Medical Center in Buffalo. As former Neurology Residency Program Director for the University at Buffalo School of Medicine where he served as Professor of Clinical Neurology and Nuclear Medicine, Dr. Meyer has trained and mentored numerous physicians in the field of Neurology. At the University of Michigan, Dr. Meyer studied GABA receptors in Alzheimer's Disease and concluded they were preserved, even in areas of dysfunctional posterior parietal cortex. As the Cole Neuroscience Foundation Investigator at the University of Tennessee, Dr. Meyer conducted some of the earliest studies on the use of PET in acute stroke, and developed techniques for PET radio-nuclide angiography, and made the first auto-radiographic demonstration of magnetic reduction of positron range, and later performed original research on the potential use of positron emitters for tumor radiotherapy.